REACTION: "The problem with ever-changing Transport Secretaries is that transport is about long-term planning. You cannot change things overnight.'' - AA president Edmund King reflects on the arrival of the sixth Transport Secretary in five years.
REACTION: "Justine Greening is a victim of intense aviation lobbying over airport expansion and an economic argument that simply doesn't add up. She's been shunted out of her transport job because of her opposition to a third runway at Heathrow." - Andy Atkins, executive director of Friends of the Earth.
It is understood that David Laws will become an education minister with an additional "roving brief" as adviser to Nick Clegg. He'll work out of the Cabinet Office.
Mr Cameron's shake-up appeared to have met with the approval of one of his most severe Tory backbench critics, Nadine Dorries. "I'm liking this reshuffle,'' she wrote on Twitter, singling out the moves for Grant Shapps, Jeremy Hunt, Chris Grayling, Maria Miller and Theresa Villiers.
REACTION: "On Sunday David Cameron promised to 'cut through the dither', but today he was too weak to move Iain Duncan Smith from the Department of Work and Pensions and was forced to back down. Jeremy Hunt, the man who broke the ministerial code and failed to stand up to News Corporation, is now in charge of the NHS, our most cherished national institution. This reshuffle isn't a fresh start - it's more of the same from an out of touch and failing Government that stands up for the wrong people.'' - Labour frontbencher Michael Dugher.
CONFIRMED: Mark Prisk has been moved from business minister to replace Grant Shapps as housing minister.
REACTION: "Whatever challenges the ministry faces, it has a fundamental obligation to ensure that everybody is able to access justice, regardless of their means. Mr Grayling must resist adding to the already punitive cuts which the last government and coalition Government have presided over.'' - Maura McGowan QC, vice-chairman of the Bar.
BREAKING NEWS: Nick Herbert, the policing minister, has just announced that he is stepping down. One wonders what he was or wasn't offered today. Herbert was a leading force behind the move to give elected individuals the power to hire and fire chief constables and set force budgets. He now appears to be one of the day's biggest losers.
REACTION: "I would have thought it is quite risky because Ken Clarke is not very well house-trained and he will say all sorts of things which will be taken as critical of or different from what George Osborne is saying and that will lead to confusion.'' - Senior Tory Peter Lilley believes the decision to hand Kenneth Clarke an economic role could undermine the Chancellor.
There's reports of another quitter. "I'm free," tweets Tory MP Michael Fabricant.